SCARB2 variants and glucocerebrosidase activity in Parkinson’s disease

SCARB2 variants and glucocerebrosidase activity in Parkinson’s disease

Mutations in glucocerebrosidase (GBA) are a common risk factor for Parkinson's disease (PD). The scavenger receptor class B member 2 (SCARB2) gene encodes a receptor responsible for the transport of glucocerebrosidase (GCase) to the lysosome. Two common SNPs in linkage disequilibrium with SCARB...

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Bibliographic Details
Main Authors: Alcalay, Roy N, Levy, Oren A, Wolf, Pavlina, Oliva, Petra, Zhang, Xiaokui Kate, Waters, Cheryl H, Fahn, Stanley, Kang, Un Jung, Liong, Christopher, Ford, Blair, Mazzoni, Pietro, Kuo, Sheng, Johnson, Amelie, Xiong, Lan, Rouleau, Guy A, Chung, Wendy K, Marder, Karen S, Gan-Or, Ziv
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838276/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838276/

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