S-Adenosylmethionine suppresses the expression of Smad3/4 in activated human hepatic stellate cells via Rac1 promoter methylation

S-Adenosylmethionine suppresses the expression of Smad3/4 in activated human hepatic stellate cells via Rac1 promoter methylation

The aim of the present study was to investigate whether S-adenosylmethionine (SAM) was able to suppress activated human hepatic stellate cells (HSCs). Human LX-2 HSCs were cultured with SAM or NSC23766, and were transfected with plasmids encoding ras-related C3 botulinum toxin substrate 1 (Rac1) pro...

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Bibliographic Details
Main Authors: BIAN, KANGQI, ZHANG, FENG, WANG, TINGTING, ZOU, XIAOPING, DUAN, XUHONG, CHEN, GUANGXIA, ZHUGE, YUZHENG
Format: Online
Language:English
Published: D.A. Spandidos 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838126/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838126/

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