The Influence of the Global Gene Expression Shift on Downstream Analyses

The assumption that total abundance of RNAs in a cell is roughly the same in different cells is underlying most studies based on gene expression analyses. But experiments have shown that changes in the expression of some master regulators such as c-MYC can cause global shift in the expression of alm...

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Bibliographic Details
Main Authors: Xu, Qifeng, Zhang, Xuegong
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836657/