Fast and sensitive mapping of nanopore sequencing reads with GraphMap

Realizing the democratic promise of nanopore sequencing requires the development of new bioinformatics approaches to deal with its specific error characteristics. Here we present GraphMap, a mapping algorithm designed to analyse nanopore sequencing reads, which progressively refines candidate alignm...

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Bibliographic Details
Main Authors: Sović, Ivan, Šikić, Mile, Wilm, Andreas, Fenlon, Shannon Nicole, Chen, Swaine, Nagarajan, Niranjan
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835549/