High glucose inhibits osteogenic differentiation through the BMP signaling pathway in bone mesenchymal stem cells in mice

Patients with diabetes tend to have an increased risk of osteoporosis that may be related to hyperglycemia. In vitro evidence has shown that high glucose can affect the proliferation and osteogenic differentiation of mesenchymal stem cells (MSCs). Tissue regeneration depends mainly on MSCs. However,...

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Bibliographic Details
Main Authors: Wang, Juncheng, Wang, Bin, Li, Ying, Wang, Dongsheng, Lingling, E, Bai, Yang, Liu, Hongchen
Format: Online
Language:English
Published: Leibniz Research Centre for Working Environment and Human Factors 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834668/