A simple and general strategy for generating frequency-anticorrelated photon pairs

Currently, two-photon excitation microscopy is the method of choice for imaging living cells within thick specimen. A remaining problem for this technique is the damage caused by the high photon flux in the excitation region. To reduce the required flux, a promising solution is to use highly frequen...

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Main Authors: Zhang, Xin, Xu, Chang, Ren, Zhongzhou
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834487/
id pubmed-4834487
recordtype oai_dc
spelling pubmed-48344872016-04-27 A simple and general strategy for generating frequency-anticorrelated photon pairs Zhang, Xin Xu, Chang Ren, Zhongzhou Article Currently, two-photon excitation microscopy is the method of choice for imaging living cells within thick specimen. A remaining problem for this technique is the damage caused by the high photon flux in the excitation region. To reduce the required flux, a promising solution is to use highly frequency-anticorrelated photon pairs, which are known to induce two-photon transitions much more efficiently. It is still an open question what the best scheme is for generating such photon pairs. Here we propose one simple general strategy for this task. As an example, we show explicitly that this general strategy can be realized faithfully within the widely applicable coherently pumped Jaynes-Cummings model. It is shown quantitatively that this strategy can generate highly frequency-anticorrelated photon pairs which can dramatically enhance two-photon excitation efficiency. We believe the proposed strategy can guide new designs for generating frequency-anticorrelated photon pairs. Nature Publishing Group 2016-04-18 /pmc/articles/PMC4834487/ /pubmed/27087255 http://dx.doi.org/10.1038/srep24509 Text en Copyright © 2016, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Zhang, Xin
Xu, Chang
Ren, Zhongzhou
spellingShingle Zhang, Xin
Xu, Chang
Ren, Zhongzhou
A simple and general strategy for generating frequency-anticorrelated photon pairs
author_facet Zhang, Xin
Xu, Chang
Ren, Zhongzhou
author_sort Zhang, Xin
title A simple and general strategy for generating frequency-anticorrelated photon pairs
title_short A simple and general strategy for generating frequency-anticorrelated photon pairs
title_full A simple and general strategy for generating frequency-anticorrelated photon pairs
title_fullStr A simple and general strategy for generating frequency-anticorrelated photon pairs
title_full_unstemmed A simple and general strategy for generating frequency-anticorrelated photon pairs
title_sort simple and general strategy for generating frequency-anticorrelated photon pairs
description Currently, two-photon excitation microscopy is the method of choice for imaging living cells within thick specimen. A remaining problem for this technique is the damage caused by the high photon flux in the excitation region. To reduce the required flux, a promising solution is to use highly frequency-anticorrelated photon pairs, which are known to induce two-photon transitions much more efficiently. It is still an open question what the best scheme is for generating such photon pairs. Here we propose one simple general strategy for this task. As an example, we show explicitly that this general strategy can be realized faithfully within the widely applicable coherently pumped Jaynes-Cummings model. It is shown quantitatively that this strategy can generate highly frequency-anticorrelated photon pairs which can dramatically enhance two-photon excitation efficiency. We believe the proposed strategy can guide new designs for generating frequency-anticorrelated photon pairs.
publisher Nature Publishing Group
publishDate 2016
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834487/
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