Recessive mutations in the cancer gene Ataxia Telangiectasia Mutated (ATM), at a locus previously associated with metformin response, cause dysglycaemia and insulin resistance

Recessive mutations in the cancer gene Ataxia Telangiectasia Mutated (ATM), at a locus previously associated with metformin response, cause dysglycaemia and insulin resistance

In a genome‐wide association study in 2011, our group identified Ataxia Telangiectasia Mutated (ATM) as a potential candidate gene associated with glycaemic response to metformin.In this study, we investigate the role of ATM in carbohydrate metabolism by performing an oral glucose tolerance test in...

Full description

Bibliographic Details
Main Authors: Connelly, P. J., Smith, N., Chadwick, R., Exley, A. R., Shneerson, J. M., Pearson, E. R.
Format: Online
Language:English
Published: John Wiley and Sons Inc. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832393/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832393/

Similar Items