Evaluation of Hybridization Capture Versus Amplicon‐Based Methods for Whole‐Exome Sequencing

Evaluation of Hybridization Capture Versus Amplicon‐Based Methods for Whole‐Exome Sequencing

Next‐generation sequencing has aided characterization of genomic variation. While whole‐genome sequencing may capture all possible mutations, whole‐exome sequencing remains cost‐effective and captures most phenotype‐altering mutations. Initial strategies for exome enrichment utilized a hybridization...

Full description

Bibliographic Details
Main Authors: Samorodnitsky, Eric, Jewell, Benjamin M., Hagopian, Raffi, Miya, Jharna, Wing, Michele R., Lyon, Ezra, Damodaran, Senthilkumar, Bhatt, Darshna, Reeser, Julie W., Datta, Jharna, Roychowdhury, Sameek
Format: Online
Language:English
Published: John Wiley and Sons Inc. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832303/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832303/

Similar Items