Novel Roles for Peroxynitrite in Angiotensin II and CaMKII Signaling

Novel Roles for Peroxynitrite in Angiotensin II and CaMKII Signaling

Ca2+/calmodulin-dependent protein kinase II (CaMKII) oxidation controls excitability and viability. While hydrogen peroxide (H2O2) affects Ca2+-activated CaMKII in vitro, Angiotensin II (Ang II)-induced CaMKIIδ signaling in cardiomyocytes is Ca2+ independent and requires NADPH oxidase-derived supero...

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Bibliographic Details
Main Authors: Zhou, Chaoming, Ramaswamy, Swarna S., Johnson, Derrick E., Vitturi, Dario A., Schopfer, Franciso J., Freeman, Bruce A., Hudmon, Andy, Levitan, Edwin S.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832198/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832198/

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