MicroRNA 139-5p coordinates APLNR-CXCR4 crosstalk during vascular maturation

G protein-coupled receptor (GPCR) signalling, including that involving apelin (APLN) and its receptor APLNR, is known to be important in vascular development. How this ligand–receptor pair regulates the downstream signalling cascades in this context remains poorly understood. Here, we show that mice...

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Bibliographic Details
Main Authors: Papangeli, Irinna, Kim, Jongmin, Maier, Inna, Park, Saejeong, Lee, Aram, Kang, Yujung, Tanaka, Keiichiro, Khan, Omar F., Ju, Hyekyung, Kojima, Yoko, Red-Horse, Kristy, Anderson, Daniel G., Siekmann, Arndt F., Chun, Hyung J.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832062/