MicroRNA‐21 induces 5‐fluorouracil resistance in human pancreatic cancer cells by regulating PTEN and PDCD4
Pancreatic cancer patients are often resistant to chemotherapy treatment, which results in poor prognosis. The objective of this study was to delineate the mechanism by which miR‐21 induces drug resistance to 5‐fluorouracil (5‐FU) in human pancreatic cancer cells (PATU8988 and PANC‐1). We report tha...
Main Authors: | , , , , , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
John Wiley and Sons Inc.
2016
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831288/ |