Mosquito Passage Dramatically Changes var Gene Expression in Controlled Human Plasmodium falciparum Infections

Mosquito Passage Dramatically Changes var Gene Expression in Controlled Human Plasmodium falciparum Infections

Virulence of the most deadly malaria parasite Plasmodium falciparum is linked to the variant surface antigen PfEMP1, which is encoded by about 60 var genes per parasite genome. Although the expression of particular variants has been associated with different clinical outcomes, little is known about...

Full description

Bibliographic Details
Main Authors: Bachmann, Anna, Petter, Michaela, Krumkamp, Ralf, Esen, Meral, Held, Jana, Scholz, Judith A. M., Li, Tao, Sim, B. Kim Lee, Hoffman, Stephen L., Kremsner, Peter G., Mordmüller, Benjamin, Duffy, Michael F., Tannich, Egbert
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829248/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829248/

Similar Items