Improvement of Neuroenergetics by Hypertonic Lactate Therapy in Patients with Traumatic Brain Injury Is Dependent on Baseline Cerebral Lactate/Pyruvate Ratio

Energy dysfunction is associated with worse prognosis after traumatic brain injury (TBI). Recent data suggest that hypertonic sodium lactate infusion (HL) improves energy metabolism after TBI. Here, we specifically examined whether the efficacy of HL (3h infusion, 30–40 μmol/kg/min) in improving bra...

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Bibliographic Details
Main Authors: Quintard, Hervé, Patet, Camille, Zerlauth, Jean-Baptiste, Suys, Tamarah, Bouzat, Pierre, Pellerin, Luc, Meuli, Reto, Magistretti, Pierre J., Oddo, Mauro
Format: Online
Language:English
Published: Mary Ann Liebert, Inc. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827289/