Oncolytic vaccinia virus as a vector for therapeutic sodium iodide symporter gene therapy in prostate cancer

Oncolytic strains of vaccinia virus are currently in clinical development with clear evidence of safety and promising signs of efficacy. Addition of therapeutic genes to the viral genome may increase the therapeutic efficacy of vaccinia. We evaluated the therapeutic potential of vaccinia virus expre...

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Bibliographic Details
Main Authors: Mansfield, D C, Kyula, J N, Rosenfelder, N, Chao-Chu, J, Kramer-Marek, G, Khan, A A, Roulstone, V, McLaughlin, M, Melcher, A A, Vile, R G, Pandha, H S, Khoo, V, Harrington, K J
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827015/