(2R,3S,2”R,3”R)-manniflavanone, a new gastrointestinal smooth muscle L-type calcium channel inhibitor, which underlies the spasmolytic properties of Garcinia buchananii stem bark extract

Garcinia buchananii Baker stem bark extract (GBB) is a traditional medication of diarrhea and dysentery in sub-Saharan Africa. It is believed that GBB causes gastrointestinal smooth muscle relaxation. The aim of this study was to determine whether GBB has spasmolytic actions and identify compounds u...

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Bibliographic Details
Main Authors: Balemba, Onesmo B., Stark, Timo D., Lösch, Sofie, Patterson, Savannah, McMillan, John S., Mawe, Gary M., Hofmann, Thomas
Format: Online
Language:English
Published: Japan Society of Smooth Muscle Research 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826780/