Metastatic Colon Cancer in an 18-Year-Old without Predisposing Factors
While colorectal carcinoma is a common gastrointestinal cancer in adults, it is rare in pediatrics with an incidence of 1 : 1,000,000 and represents a fraction of neoplasms encountered in children. Malignant neoplasms represent a major cause of mortality in the pediatric age group. While presenting...
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pubmed-48266872016-04-24 Metastatic Colon Cancer in an 18-Year-Old without Predisposing Factors Mirchandani, Divya Kulpa, Jolanta Khawar, Nayaab Kochin, Israel Narula, Pramod Sundaram, Revathy Case Report While colorectal carcinoma is a common gastrointestinal cancer in adults, it is rare in pediatrics with an incidence of 1 : 1,000,000 and represents a fraction of neoplasms encountered in children. Malignant neoplasms represent a major cause of mortality in the pediatric age group. While presenting with weight loss, iron deficiency, rectal bleeding, abdominal pain, and change in bowel habits, or symptoms similar to acute appendicitis, the working diagnosis may be considered to be anorexia. This case illustrates the importance of considering colon cancer among other disease entities as a cause of unintentional weight loss in adolescents. While this is a rare occurrence in the pediatric population, significant unintentional weight loss with altered bowel habits should prompt a search for underlying malignancy—even in the absence of a positive family history or predisposing cancer syndromes. Hindawi Publishing Corporation 2016 2016-03-27 /pmc/articles/PMC4826687/ /pubmed/27110420 http://dx.doi.org/10.1155/2016/7820367 Text en Copyright © 2016 Divya Mirchandani et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
repository_type |
Open Access Journal |
institution_category |
Foreign Institution |
institution |
US National Center for Biotechnology Information |
building |
NCBI PubMed |
collection |
Online Access |
language |
English |
format |
Online |
author |
Mirchandani, Divya Kulpa, Jolanta Khawar, Nayaab Kochin, Israel Narula, Pramod Sundaram, Revathy |
spellingShingle |
Mirchandani, Divya Kulpa, Jolanta Khawar, Nayaab Kochin, Israel Narula, Pramod Sundaram, Revathy Metastatic Colon Cancer in an 18-Year-Old without Predisposing Factors |
author_facet |
Mirchandani, Divya Kulpa, Jolanta Khawar, Nayaab Kochin, Israel Narula, Pramod Sundaram, Revathy |
author_sort |
Mirchandani, Divya |
title |
Metastatic Colon Cancer in an 18-Year-Old without Predisposing Factors |
title_short |
Metastatic Colon Cancer in an 18-Year-Old without Predisposing Factors |
title_full |
Metastatic Colon Cancer in an 18-Year-Old without Predisposing Factors |
title_fullStr |
Metastatic Colon Cancer in an 18-Year-Old without Predisposing Factors |
title_full_unstemmed |
Metastatic Colon Cancer in an 18-Year-Old without Predisposing Factors |
title_sort |
metastatic colon cancer in an 18-year-old without predisposing factors |
description |
While colorectal carcinoma is a common gastrointestinal cancer in adults, it is rare in pediatrics with an incidence of 1 : 1,000,000 and represents a fraction of neoplasms encountered in children. Malignant neoplasms represent a major cause of mortality in the pediatric age group. While presenting with weight loss, iron deficiency, rectal bleeding, abdominal pain, and change in bowel habits, or symptoms similar to acute appendicitis, the working diagnosis may be considered to be anorexia. This case illustrates the importance of considering colon cancer among other disease entities as a cause of unintentional weight loss in adolescents. While this is a rare occurrence in the pediatric population, significant unintentional weight loss with altered bowel habits should prompt a search for underlying malignancy—even in the absence of a positive family history or predisposing cancer syndromes. |
publisher |
Hindawi Publishing Corporation |
publishDate |
2016 |
url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826687/ |
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1613564414130126848 |