ΔF508 CFTR interactome remodeling promotes rescue of Cystic Fibrosis

ΔF508 CFTR interactome remodeling promotes rescue of Cystic Fibrosis

Deletion of phenylalanine 508 of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) is the major cause of Cystic Fibrosis (CF), one of the most common inherited childhood diseases. The mutated CFTR anion channel is not fully glycosylated and shows minimal activity in bronchial epithelial...

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Bibliographic Details
Main Authors: Pankow, Sandra, Bamberger, Casimir, Calzolari, Diego, Martínez-Bartolomé, Salvador, Lavallée-Adam, Mathieu, Balch, William E., Yates, John R.
Format: Online
Language:English
Published: 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826614/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826614/

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