Autophagy is involved in TGF-β1-induced protective mechanisms and formation of cancer-associated fibroblasts phenotype in tumor microenvironment

Autophagy is involved in TGF-β1-induced protective mechanisms and formation of cancer-associated fibroblasts phenotype in tumor microenvironment

Transforming growth factor-β1 (TGF-β1) present in tumor microenvironment acts in a coordinated fashion to either suppress or promote tumor development. However, the molecular mechanisms underlying the effects of TGF-β1 on tumor microenvironment are not well understood. Our clinical data showed a pos...

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Bibliographic Details
Main Authors: Liu, Fang-Lan, Mo, En-Pan, Yang, Liu, Du, Jun, Wang, Hong-Sheng, Zhang, Huan, Kurihara, Hiroshi, Xu, Jun, Cai, Shao-Hui
Format: Online
Language:English
Published: Impact Journals LLC 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826194/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826194/

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