Sialic Acid Glycobiology Unveils Trypanosoma cruzi Trypomastigote Membrane Physiology

Trypanosoma cruzi, the flagellate protozoan agent of Chagas disease or American trypanosomiasis, is unable to synthesize sialic acids de novo. Mucins and trans-sialidase (TS) are substrate and enzyme, respectively, of the glycobiological system that scavenges sialic acid from the host in a crucial...

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Bibliographic Details
Main Authors: Lantos, Andrés B., Carlevaro, Giannina, Araoz, Beatriz, Ruiz Diaz, Pablo, Camara, María de los Milagros, Buscaglia, Carlos A., Bossi, Mariano, Yu, Hai, Chen, Xi, Bertozzi, Carolyn R., Mucci, Juan, Campetella, Oscar
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825991/