HSV vector-mediated GAD67 suppresses neuropathic pain induced by perineural HIV gp120 in rats through inhibition of ROS and Wnt5a

Human immunodeficiency virus (HIV)-related neuropathic pain is a debilitating chronic condition that is severe and unrelenting. Despite the extensive research, the exact neuropathological mechanisms remain unknown, which hinders our ability to develop effective treatments. Loss of GABAergic tone may...

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Bibliographic Details
Main Authors: Kanda, Hirotsugu, Kanao, Megumi, Liu, Shue, Yi, Hyun, Iida, Takafumi, Levitt, Roy C, Candiotti, Keith A, Lubarsky, David A, Hao, Shuanglin
Format: Online
Language:English
Published: 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824655/