Facile Synthesis of Photofunctional Nanolayer Coatings on Titanium Substrates

We developed a two-step chemical bonding process using photosensitizer molecules to fabricate photofunctional nanolayer coatings on hematoporphyrin- (HP-) coated Ti substrates. In the first step, 3-aminopropyltriethoxysilane was covalently functionalized onto the surface of the Ti substrates to prov...

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Main Authors:	Choi, Kyong-Hoon, Kim, Jung-Gil, Kang, Byungman, Kim, Ho-Joong, Park, Bong Joo
Format:	Online
Language:	English
Published:	Hindawi Publishing Corporation 2016
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823491/

id	pubmed-4823491
recordtype	oai_dc
spelling	pubmed-48234912016-04-24 Facile Synthesis of Photofunctional Nanolayer Coatings on Titanium Substrates Choi, Kyong-Hoon Kim, Jung-Gil Kang, Byungman Kim, Ho-Joong Park, Bong Joo Research Article We developed a two-step chemical bonding process using photosensitizer molecules to fabricate photofunctional nanolayer coatings on hematoporphyrin- (HP-) coated Ti substrates. In the first step, 3-aminopropyltriethoxysilane was covalently functionalized onto the surface of the Ti substrates to provide heterogeneous sites for immobilizing the HP molecules. Then, HP molecules with carboxyl groups were chemically attached to the amine-terminated nanolayer coatings via a carbodiimide coupling reaction. The microstructure and elemental and phase composition of the HP-coated Ti substrates were investigated using field-emission scanning electron microscopy and energy-dispersive X-ray spectrometry. The photophysical properties of the photofunctional nanolayer coatings were confirmed using reflectance ultraviolet-visible absorption and emission spectrophotometry. The singlet oxygen generation efficiency of the photofunctional nanolayer coatings was determined using the decomposition reaction of 1,3-diphenylisobenzofuran. The HP-coated Ti substrates exhibited good biocompatibility without any cytotoxicity, and these nanolayer coatings generated singlet oxygen, which can kill microorganisms using only visible light. Hindawi Publishing Corporation 2016 2016-03-24 /pmc/articles/PMC4823491/ /pubmed/27110564 http://dx.doi.org/10.1155/2016/4318917 Text en Copyright © 2016 Kyong-Hoon Choi et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Choi, Kyong-Hoon Kim, Jung-Gil Kang, Byungman Kim, Ho-Joong Park, Bong Joo
spellingShingle	Choi, Kyong-Hoon Kim, Jung-Gil Kang, Byungman Kim, Ho-Joong Park, Bong Joo Facile Synthesis of Photofunctional Nanolayer Coatings on Titanium Substrates
author_facet	Choi, Kyong-Hoon Kim, Jung-Gil Kang, Byungman Kim, Ho-Joong Park, Bong Joo
author_sort	Choi, Kyong-Hoon
title	Facile Synthesis of Photofunctional Nanolayer Coatings on Titanium Substrates
title_short	Facile Synthesis of Photofunctional Nanolayer Coatings on Titanium Substrates
title_full	Facile Synthesis of Photofunctional Nanolayer Coatings on Titanium Substrates
title_fullStr	Facile Synthesis of Photofunctional Nanolayer Coatings on Titanium Substrates
title_full_unstemmed	Facile Synthesis of Photofunctional Nanolayer Coatings on Titanium Substrates
title_sort	facile synthesis of photofunctional nanolayer coatings on titanium substrates
description	We developed a two-step chemical bonding process using photosensitizer molecules to fabricate photofunctional nanolayer coatings on hematoporphyrin- (HP-) coated Ti substrates. In the first step, 3-aminopropyltriethoxysilane was covalently functionalized onto the surface of the Ti substrates to provide heterogeneous sites for immobilizing the HP molecules. Then, HP molecules with carboxyl groups were chemically attached to the amine-terminated nanolayer coatings via a carbodiimide coupling reaction. The microstructure and elemental and phase composition of the HP-coated Ti substrates were investigated using field-emission scanning electron microscopy and energy-dispersive X-ray spectrometry. The photophysical properties of the photofunctional nanolayer coatings were confirmed using reflectance ultraviolet-visible absorption and emission spectrophotometry. The singlet oxygen generation efficiency of the photofunctional nanolayer coatings was determined using the decomposition reaction of 1,3-diphenylisobenzofuran. The HP-coated Ti substrates exhibited good biocompatibility without any cytotoxicity, and these nanolayer coatings generated singlet oxygen, which can kill microorganisms using only visible light.
publisher	Hindawi Publishing Corporation
publishDate	2016
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823491/
_version_	1613563320505204736

Facile Synthesis of Photofunctional Nanolayer Coatings on Titanium Substrates

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