Placental hypoxia, endoplasmic reticulum stress and maternal endothelial sensitisation by sFLT1 in pre-eclampsia

•The concept of “placental hypoxia”.•Placental endoplasmic reticulum stress and maternal sensitivity to pre-eclampsia.•How soluble FLT1 sensitises maternal endothelium to inflammatory mediators in vitro.

Bibliographic Details
Main Author: Charnock-Jones, D. Stephen
Format: Online
Language:English
Published: Elsevier/North-Holland Biomedical Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822533/