Rac1 modulates the formation of primordial follicles by facilitating STAT3-directed Jagged1, GDF9 and BMP15 transcription in mice

The size of the primordial follicle pool determines the reproductive potential of mammalian females, and establishment of the pool is highly dependent on specific genes expression. However, the molecular mechanisms by which the essential genes are regulated coordinately to ensure primordial follicle...

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Bibliographic Details
Main Authors: Zhao, Lihua, Du, Xinhua, Huang, Kun, Zhang, Tuo, Teng, Zhen, Niu, Wanbao, Wang, Chao, Xia, Guoliang
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822123/