Neogenin recruitment of the WAVE regulatory complex maintains adherens junction stability and tension

To maintain tissue integrity during epithelial morphogenesis, adherens junctions (AJs) must resist the mechanical stresses exerted by dynamic tissue movements. Junctional stability is dependent on actomyosin contractility within the actin ring. Here we describe a novel function for the axon guidance...

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Bibliographic Details
Main Authors: Lee, Natalie K., Fok, Ka Wai, White, Amanda, Wilson, Nicole H., O'Leary, Conor J., Cox, Hayley L., Michael, Magdalene, Yap, Alpha S., Cooper, Helen M.
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821876/