Lamellipodin-Deficient Mice: A Model of Rectal Carcinoma

During a survey of clinical rectal prolapse (RP) cases in the mouse population at MIT animal research facilities, a high incidence of RP in the lamellipodin knock-out strain, C57BL/6-Raph1tm1Fbg (Lpd-/-) was documented. Upon further investigation, the Lpd-/- colony was found to be infected with mult...

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Bibliographic Details
Main Authors: Miller, Cassandra L., Muthupalani, Sureshkumar, Shen, Zeli, Drees, Frauke, Ge, Zhongming, Feng, Yan, Chen, Xiaowei, Gong, Guanyu, Nagar, Karan K., Wang, Timothy C., Gertler, Frank B., Fox, James G.
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821566/