Pairwise detection of site-specific receptor phosphorylations using single-molecule blotting

Post-translational modifications (PTMs) of receptor tyrosine kinases (RTKs) at the plasma membrane (PM) determine the signal transduction efficacy alone and in combination. However, current approaches to identify PTMs provide ensemble results, inherently overlooking combinatorial PTMs in a single po...

Full description

Bibliographic Details
Main Authors: Kim, Kyung Lock, Kim, Daehyung, Lee, Seongsil, Kim, Su-Jeong, Noh, Jung Eun, Kim, Joung-Hun, Chae, Young Chan, Lee, Jong-Bong, Ryu, Sung Ho
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820850/