Positioning of centrioles is a conserved readout of Frizzled planar cell polarity signalling

Planar cell polarity (PCP) signalling is a well-conserved developmental pathway regulating cellular orientation during development. An evolutionarily conserved pathway readout is not established and, moreover, it is thought that PCP mediated cellular responses are tissue-specific. A key PCP function...

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Bibliographic Details
Main Authors: Carvajal-Gonzalez, Jose Maria, Roman, Angel-Carlos, Mlodzik, Marek
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820615/