Regulation of protein-ligand binding affinity by hydrogen bond pairing
Receptor-ligand H-bond pairings have evolved to promote high-affinity binding by reducing competitive interference with water.
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
American Association for the Advancement of Science
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820369/ |