Distinct Structural Pathways Coordinate the Activation of AMPA Receptor-Auxiliary Subunit Complexes

Distinct Structural Pathways Coordinate the Activation of AMPA Receptor-Auxiliary Subunit Complexes

Neurotransmitter-gated ion channels adopt different gating modes to fine-tune signaling at central synapses. At glutamatergic synapses, high and low activity of AMPA receptors (AMPARs) is observed when pore-forming subunits coassemble with or without auxiliary subunits, respectively. Whether a commo...

Full description

Bibliographic Details
Main Authors: Dawe, G. Brent, Musgaard, Maria, Aurousseau, Mark R.P., Nayeem, Naushaba, Green, Tim, Biggin, Philip C., Bowie, Derek
Format: Online
Language:English
Published: Cell Press 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819453/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819453/

Similar Items