Mechanisms of Vascular Smooth Muscle Contraction and the Basis for Pharmacologic Treatment of Smooth Muscle Disorders

The smooth muscle cell directly drives the contraction of the vascular wall and hence regulates the size of the blood vessel lumen. We review here the current understanding of the molecular mechanisms by which agonists, therapeutics, and diseases regulate contractility of the vascular smooth muscle...

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Bibliographic Details
Main Authors: Brozovich, F.V., Nicholson, C.J., Degen, C.V., Gao, Yuan Z., Aggarwal, M., Morgan, K.G.
Format: Online
Language:English
Published: The American Society for Pharmacology and Experimental Therapeutics 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819215/