New Trypanosoma evansi Type B Isolates from Ethiopian Dromedary Camels

Trypanosoma (T.) evansi causes surra in various animal species in Africa, Latin America and Asia. Despite inducing important animal suffering, economic losses and being a World Animal Health Organisation (OIE) notifiable disease, surra is severely neglected in terms of awareness, control interventio...

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Main Authors:	Birhanu, Hadush, Gebrehiwot, Tadesse, Goddeeris, Bruno Maria, Büscher, Philippe, Van Reet, Nick
Format:	Online
Language:	English
Published:	Public Library of Science 2016
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818106/

id	pubmed-4818106
recordtype	oai_dc
spelling	pubmed-48181062016-04-19 New Trypanosoma evansi Type B Isolates from Ethiopian Dromedary Camels Birhanu, Hadush Gebrehiwot, Tadesse Goddeeris, Bruno Maria Büscher, Philippe Van Reet, Nick Research Article Trypanosoma (T.) evansi causes surra in various animal species in Africa, Latin America and Asia. Despite inducing important animal suffering, economic losses and being a World Animal Health Organisation (OIE) notifiable disease, surra is severely neglected in terms of awareness, control interventions and research into improved control tools. Most serological tests can only detect T. evansi type A, while molecular tests rely on detection of highly variable genes or on fragile kinetoplast DNA. Even more, the obscure T. evansi type B, first isolated decades ago in Kenya, totally escapes surveillance due to absence of reliable diagnostic tools. In the present study we isolated new type B stocks from Ethiopia, thus suggesting that this type of T. evansi is probably more widely distributed than previously thought. We further report on an alternative molecular marker for both types of T. evansi and present data on the drug sensitivity of the Ethiopian isolates. Public Library of Science 2016-04-01 /pmc/articles/PMC4818106/ /pubmed/27035661 http://dx.doi.org/10.1371/journal.pntd.0004556 Text en © 2016 Birhanu et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Birhanu, Hadush Gebrehiwot, Tadesse Goddeeris, Bruno Maria Büscher, Philippe Van Reet, Nick
spellingShingle	Birhanu, Hadush Gebrehiwot, Tadesse Goddeeris, Bruno Maria Büscher, Philippe Van Reet, Nick New Trypanosoma evansi Type B Isolates from Ethiopian Dromedary Camels
author_facet	Birhanu, Hadush Gebrehiwot, Tadesse Goddeeris, Bruno Maria Büscher, Philippe Van Reet, Nick
author_sort	Birhanu, Hadush
title	New Trypanosoma evansi Type B Isolates from Ethiopian Dromedary Camels
title_short	New Trypanosoma evansi Type B Isolates from Ethiopian Dromedary Camels
title_full	New Trypanosoma evansi Type B Isolates from Ethiopian Dromedary Camels
title_fullStr	New Trypanosoma evansi Type B Isolates from Ethiopian Dromedary Camels
title_full_unstemmed	New Trypanosoma evansi Type B Isolates from Ethiopian Dromedary Camels
title_sort	new trypanosoma evansi type b isolates from ethiopian dromedary camels
description	Trypanosoma (T.) evansi causes surra in various animal species in Africa, Latin America and Asia. Despite inducing important animal suffering, economic losses and being a World Animal Health Organisation (OIE) notifiable disease, surra is severely neglected in terms of awareness, control interventions and research into improved control tools. Most serological tests can only detect T. evansi type A, while molecular tests rely on detection of highly variable genes or on fragile kinetoplast DNA. Even more, the obscure T. evansi type B, first isolated decades ago in Kenya, totally escapes surveillance due to absence of reliable diagnostic tools. In the present study we isolated new type B stocks from Ethiopia, thus suggesting that this type of T. evansi is probably more widely distributed than previously thought. We further report on an alternative molecular marker for both types of T. evansi and present data on the drug sensitivity of the Ethiopian isolates.
publisher	Public Library of Science
publishDate	2016
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818106/
_version_	1613561139760726016

New Trypanosoma evansi Type B Isolates from Ethiopian Dromedary Camels

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