Godzilla-dependent transcytosis promotes Wingless signalling in Drosophila wing imaginal discs

The apical and basolateral membranes of epithelia are insulated from each other, preventing the transfer of extracellular proteins from one side to the other1. Thus, a signalling protein produced apically is not expected to reach basolateral receptors. Evidence suggests that Wingless, the main Droso...

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Bibliographic Details
Main Authors: Yamazaki, Yasuo, Palmer, Lucy, Alexandre, Cyrille, Kakugawa, Satoshi, Beckett, Karen, Gaugue, Isabelle, Palmer, Ruth H., Vincent, Jean-Paul
Format: Online
Language:English
Published: 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817240/