Structural Studies of Lipopolysaccharide-defective Mutants from Brucella melitensis Identify a Core Oligosaccharide Critical in Virulence*

Structural Studies of Lipopolysaccharide-defective Mutants from Brucella melitensis Identify a Core Oligosaccharide Critical in Virulence*

The structures of the lipooligosaccharides from Brucella melitensis mutants affected in the WbkD and ManBcore proteins have been fully characterized using NMR spectroscopy. The results revealed that disruption of wbkD gives rise to a rough lipopolysaccharide (R-LPS) with a complete core structure (β...

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Bibliographic Details
Main Authors: Fontana, Carolina, Conde-Álvarez, Raquel, Ståhle, Jonas, Holst, Otto, Iriarte, Maite, Zhao, Yun, Arce-Gorvel, Vilma, Hanniffy, Seán, Gorvel, Jean-Pierre, Moriyón, Ignacio, Widmalm, Göran
Format: Online
Language:English
Published: American Society for Biochemistry and Molecular Biology 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817197/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817197/

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