Doxorubicin resistant cancer cells activate myeloid-derived suppressor cells by releasing PGE2

Doxorubicin resistant cancer cells activate myeloid-derived suppressor cells by releasing PGE2

Chemotherapies often induce drug-resistance in cancer cells and simultaneously stimulate proliferation and activation of Myeloid-Derived Suppressor Cells (MDSCs) to inhibit anti-tumor T cells, thus result in poor prognosis of patients with breast cancers. To date, the mechanism underlying the expans...

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Bibliographic Details
Main Authors: Rong, Yuan, Yuan, Chun-Hui, Qu, Zhen, Zhou, Hu, Guan, Qing, Yang, Na, Leng, Xiao-Hua, Bu, Lang, Wu, Ke, Wang, Fu-Bing
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817121/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817121/

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