Effects of Perfluorooctanoic Acid on Metabolic Profiles in Brain and Liver of Mouse Revealed by a High-throughput Targeted Metabolomics Approach

Perfluorooctanoic acid (PFOA), a perfluoroalkyl acid, can result in hepatotoxicity and neurobehavioral effects in animals. The metabolome, which serves as a connection among transcriptome, proteome and toxic effects, provides pathway-based insights into effects of PFOA. Since understanding of change...

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Bibliographic Details
Main Authors: Yu, Nanyang, Wei, Si, Li, Meiying, Yang, Jingping, Li, Kan, Jin, Ling, Xie, Yuwei, Giesy, John P., Zhang, Xiaowei, Yu, Hongxia
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817033/