Therapy decisions for the symptomatic patient with metastatic castration-resistant prostate cancer

Metastatic prostate cancer continues to kill approximately 30,000 men per year. Since 2010, five new therapeutic agents have been Food and Drug Administration (FDA) approved to treat metastatic castration-resistant prostate cancer (mCRPC). With the increasing number of therapies available to clinici...

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Main Authors: Markowski, Mark C, Pienta, Kenneth J
Format: Online
Language:English
Published: Medknow Publications & Media Pvt Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814966/
id pubmed-4814966
recordtype oai_dc
spelling pubmed-48149662016-04-19 Therapy decisions for the symptomatic patient with metastatic castration-resistant prostate cancer Markowski, Mark C Pienta, Kenneth J Invited Opinion Metastatic prostate cancer continues to kill approximately 30,000 men per year. Since 2010, five new therapeutic agents have been Food and Drug Administration (FDA) approved to treat metastatic castration-resistant prostate cancer (mCRPC). With the increasing number of therapies available to clinicians, the most effective sequence in which to implement these treatments remains unknown. The presence or absence of symptoms (i.e., bony pain, visceral crisis) is a key parameter that informs the decision-making process regarding therapy. Treatment algorithms based on: 1) asymptomatic/minimal symptoms, 2) moderate symptoms or chemotherapy ineligible or 3) symptomatic disease need to be developed. Medknow Publications & Media Pvt Ltd 2015 2015-04-10 /pmc/articles/PMC4814966/ /pubmed/25865849 http://dx.doi.org/10.4103/1008-682X.150843 Text en Copyright: © Asian Journal of Andrology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Markowski, Mark C
Pienta, Kenneth J
spellingShingle Markowski, Mark C
Pienta, Kenneth J
Therapy decisions for the symptomatic patient with metastatic castration-resistant prostate cancer
author_facet Markowski, Mark C
Pienta, Kenneth J
author_sort Markowski, Mark C
title Therapy decisions for the symptomatic patient with metastatic castration-resistant prostate cancer
title_short Therapy decisions for the symptomatic patient with metastatic castration-resistant prostate cancer
title_full Therapy decisions for the symptomatic patient with metastatic castration-resistant prostate cancer
title_fullStr Therapy decisions for the symptomatic patient with metastatic castration-resistant prostate cancer
title_full_unstemmed Therapy decisions for the symptomatic patient with metastatic castration-resistant prostate cancer
title_sort therapy decisions for the symptomatic patient with metastatic castration-resistant prostate cancer
description Metastatic prostate cancer continues to kill approximately 30,000 men per year. Since 2010, five new therapeutic agents have been Food and Drug Administration (FDA) approved to treat metastatic castration-resistant prostate cancer (mCRPC). With the increasing number of therapies available to clinicians, the most effective sequence in which to implement these treatments remains unknown. The presence or absence of symptoms (i.e., bony pain, visceral crisis) is a key parameter that informs the decision-making process regarding therapy. Treatment algorithms based on: 1) asymptomatic/minimal symptoms, 2) moderate symptoms or chemotherapy ineligible or 3) symptomatic disease need to be developed.
publisher Medknow Publications & Media Pvt Ltd
publishDate 2015
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814966/
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