Strategically targeting MYC in cancer

MYC is a major driver of cancer cell growth and mediates a transcriptional program spanning cell growth, the cell cycle, metabolism, and cell survival. Many efforts have been made to deliberately target MYC for cancer therapy. A variety of compounds have been generated to inhibit MYC function or sta...

Full description

Bibliographic Details
Main Authors: Posternak, Valeriya, Cole, Michael D.
Format: Online
Language:English
Published: F1000Research 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813636/