Mit1 Transcription Factor Mediates Methanol Signaling and Regulates the Alcohol Oxidase 1 (AOX1) Promoter in Pichia pastoris*

The alcohol oxidase 1 (AOX1) promoter (PAOX1) of Pichia pastoris is the most powerful and commonly used promoter for driving protein expression. However, mechanisms regulating its transcriptional activity are unclear. Here, we identified a Zn(II)2Cys6-type methanol-induced transcription factor 1 (Mi...

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Bibliographic Details
Main Authors: Wang, Xiaolong, Wang, Qi, Wang, Jinjia, Bai, Peng, Shi, Lei, Shen, Wei, Zhou, Mian, Zhou, Xiangshan, Zhang, Yuanxing, Cai, Menghao
Format: Online
Language:English
Published: American Society for Biochemistry and Molecular Biology 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813576/