Phosphorylated 4EBP1 is associated with tumor progression and poor prognosis in Xp11.2 translocation renal cell carcinoma

Phosphorylated 4EBP1 is associated with tumor progression and poor prognosis in Xp11.2 translocation renal cell carcinoma

Two main signaling pathways, PI3K-AKT-mTOR and RAS-MAPK, are involved in transmitting the proliferative signals which play critical roles in human cancers. However, the functions of these pathways in Xp11.2 RCC remain undefined. This study aimed to explore the expression of mTOR and MAPK cascades in...

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Bibliographic Details
Main Authors: Qu, Yuanyuan, Zhao, Rui, Wang, Hongkai, Chang, Kun, Yang, Xiaoqun, Zhou, Xiaoyan, Dai, Bo, Zhu, Yao, Shi, Guohai, Zhang, Hailiang, Ye, Dingwei
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812307/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812307/

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