Two echinocandin-resistant Candida glabrata FKS mutants from South Africa

Echinocandins are recommended as first-line agents to treat invasive infections caused by Candida glabrata since this organism is inherently less susceptible to azoles. However, resistance to echinocandins has been described in C. glabrata due to amino acid changes in the hotspot regions of the FKS1...

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Bibliographic Details
Main Authors: Naicker, Serisha D., Magobo, Rindidzani E., Zulu, Thokozile G., Maphanga, Tsidiso G., Luthuli, Nkosinathi, Lowman, Warren, Govender, Nelesh P.
Format: Online
Language:English
Published: Elsevier 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811853/