Time-dependent low-field MRI characteristics of canine blood: an in vitro study

This study was conducted to assess time-sensitive magnetic resonance (MR) changes in canine blood using low-field MR. Arterial and venous blood samples were collected from eight healthy beagle dogs. Samples were placed in 5-mL tubes and imaged within 3 hours of collection at 1 day intervals from day...

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Main Authors:	Jeong, Jimo, Park, Sangjun, Jeong, Eunseok, Kim, Namsoo, Kim, Minsu, Jung, Yechan, Cho, Youngkwon, Lee, Kichang
Format:	Online
Language:	English
Published:	The Korean Society of Veterinary Science 2016
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808634/

id	pubmed-4808634
recordtype	oai_dc
spelling	pubmed-48086342016-04-05 Time-dependent low-field MRI characteristics of canine blood: an in vitro study Jeong, Jimo Park, Sangjun Jeong, Eunseok Kim, Namsoo Kim, Minsu Jung, Yechan Cho, Youngkwon Lee, Kichang Original Article This study was conducted to assess time-sensitive magnetic resonance (MR) changes in canine blood using low-field MR. Arterial and venous blood samples were collected from eight healthy beagle dogs. Samples were placed in 5-mL tubes and imaged within 3 hours of collection at 1 day intervals from day 1 to day 30. The following sequences were used: T1-weighted (T1W), T2-weighted (T2W), fluid-attenuated inversion recovery (FLAIR), short tau inversion recovery (STIR), and T2-star gradient-echo (T2*-GRE). Visual comparison of the images revealed that four relatively homogenous blood clots and twelve heterogeneous blood clots developed. The margination of the clot and plasma changed significantly on day 2 and day 13. On day 2, heterogeneous blood clots were differentiated into 2 to 3 signal layers in the T2W, T1W, and especially the STIR images. Hypointense signal layers were also detected in the blood clots in STIR images, which have T2 hypo, FLAIR hypo, and T1 hyper intense signals. In all images, these signal layers remained relatively unchanged until day 13. Overall, the results suggest that hematomas are complex on low-field MRI. Accordingly, it may not be feasible to accurately characterize hemorrhages and predict clot age based on low-field MRI. The Korean Society of Veterinary Science 2016-03 2016-03-22 /pmc/articles/PMC4808634/ /pubmed/27051346 http://dx.doi.org/10.4142/jvs.2016.17.1.103 Text en © 2016 The Korean Society of Veterinary Science. http://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Jeong, Jimo Park, Sangjun Jeong, Eunseok Kim, Namsoo Kim, Minsu Jung, Yechan Cho, Youngkwon Lee, Kichang
spellingShingle	Jeong, Jimo Park, Sangjun Jeong, Eunseok Kim, Namsoo Kim, Minsu Jung, Yechan Cho, Youngkwon Lee, Kichang Time-dependent low-field MRI characteristics of canine blood: an in vitro study
author_facet	Jeong, Jimo Park, Sangjun Jeong, Eunseok Kim, Namsoo Kim, Minsu Jung, Yechan Cho, Youngkwon Lee, Kichang
author_sort	Jeong, Jimo
title	Time-dependent low-field MRI characteristics of canine blood: an in vitro study
title_short	Time-dependent low-field MRI characteristics of canine blood: an in vitro study
title_full	Time-dependent low-field MRI characteristics of canine blood: an in vitro study
title_fullStr	Time-dependent low-field MRI characteristics of canine blood: an in vitro study
title_full_unstemmed	Time-dependent low-field MRI characteristics of canine blood: an in vitro study
title_sort	time-dependent low-field mri characteristics of canine blood: an in vitro study
description	This study was conducted to assess time-sensitive magnetic resonance (MR) changes in canine blood using low-field MR. Arterial and venous blood samples were collected from eight healthy beagle dogs. Samples were placed in 5-mL tubes and imaged within 3 hours of collection at 1 day intervals from day 1 to day 30. The following sequences were used: T1-weighted (T1W), T2-weighted (T2W), fluid-attenuated inversion recovery (FLAIR), short tau inversion recovery (STIR), and T2-star gradient-echo (T2*-GRE). Visual comparison of the images revealed that four relatively homogenous blood clots and twelve heterogeneous blood clots developed. The margination of the clot and plasma changed significantly on day 2 and day 13. On day 2, heterogeneous blood clots were differentiated into 2 to 3 signal layers in the T2W, T1W, and especially the STIR images. Hypointense signal layers were also detected in the blood clots in STIR images, which have T2 hypo, FLAIR hypo, and T1 hyper intense signals. In all images, these signal layers remained relatively unchanged until day 13. Overall, the results suggest that hematomas are complex on low-field MRI. Accordingly, it may not be feasible to accurately characterize hemorrhages and predict clot age based on low-field MRI.
publisher	The Korean Society of Veterinary Science
publishDate	2016
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808634/
_version_	1613557966146895872

Time-dependent low-field MRI characteristics of canine blood: an in vitro study

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