Mouse SAMHD1 Has Antiretroviral Activity and Suppresses a Spontaneous Cell-Intrinsic Antiviral Response

Mouse SAMHD1 Has Antiretroviral Activity and Suppresses a Spontaneous Cell-Intrinsic Antiviral Response

Aicardi-Goutières syndrome (AGS), a hereditary autoimmune disease, clinically and biochemically overlaps with systemic lupus erythematosus (SLE) and, like SLE, is characterized by spontaneous type I interferon (IFN) production. The finding that defects of intracellular nucleases cause AGS led to the...

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Bibliographic Details
Main Authors: Behrendt, Rayk, Schumann, Tina, Gerbaulet, Alexander, Nguyen, Laura A., Schubert, Nadja, Alexopoulou, Dimitra, Berka, Ursula, Lienenklaus, Stefan, Peschke, Katrin, Gibbert, Kathrin, Wittmann, Sabine, Lindemann, Dirk, Weiss, Siegfried, Dahl, Andreas, Naumann, Ronald, Dittmer, Ulf, Kim, Baek, Mueller, Werner, Gramberg, Thomas, Roers, Axel
Format: Online
Language:English
Published: 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807655/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807655/

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