Genome-wide siRNA Screening at Biosafety Level 4 Reveals a Crucial Role for Fibrillarin in Henipavirus Infection

Genome-wide siRNA Screening at Biosafety Level 4 Reveals a Crucial Role for Fibrillarin in Henipavirus Infection

Hendra and Nipah viruses (genus Henipavirus, family Paramyxoviridae) are highly pathogenic bat-borne viruses. The need for high biocontainment when studying henipaviruses has hindered the development of therapeutics and knowledge of the viral infection cycle. We have performed a genome-wide siRNA sc...

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Bibliographic Details
Main Authors: Deffrasnes, Celine, Marsh, Glenn A., Foo, Chwan Hong, Rootes, Christina L., Gould, Cathryn M., Grusovin, Julian, Monaghan, Paul, Lo, Michael K., Tompkins, S. Mark, Adams, Timothy E., Lowenthal, John W., Simpson, Kaylene J., Stewart, Cameron R., Bean, Andrew G. D., Wang, Lin-Fa
Format: Online
Language:English
Published: Public Library of Science 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806981/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806981/

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