Cross-Neutralization between Human and African Bat Mumps Viruses

Cross-Neutralization between Human and African Bat Mumps Viruses

Recently, a new paramyxovirus closely related to human mumps virus (MuV) was detected in bats. We generated recombinant MuVs carrying either or both of the fusion and hemagglutinin-neuraminidase bat virus glycoproteins. These viruses showed replication kinetics similar to human MuV in cultured cells...

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Main Authors: Katoh, Hiroshi, Kubota, Toru, Ihara, Toshiaki, Maeda, Ken, Takeda, Makoto, Kidokoro, Minoru
Format: Online
Language:English
Published: Centers for Disease Control and Prevention 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806932/
id pubmed-4806932
recordtype oai_dc
spelling pubmed-48069322016-04-01 Cross-Neutralization between Human and African Bat Mumps Viruses Katoh, Hiroshi Kubota, Toru Ihara, Toshiaki Maeda, Ken Takeda, Makoto Kidokoro, Minoru Dispatch Recently, a new paramyxovirus closely related to human mumps virus (MuV) was detected in bats. We generated recombinant MuVs carrying either or both of the fusion and hemagglutinin-neuraminidase bat virus glycoproteins. These viruses showed replication kinetics similar to human MuV in cultured cells and were neutralized efficiently by serum from healthy humans. Centers for Disease Control and Prevention 2016-04 /pmc/articles/PMC4806932/ /pubmed/26982800 http://dx.doi.org/10.3201/eid2204.151116 Text en
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Katoh, Hiroshi
Kubota, Toru
Ihara, Toshiaki
Maeda, Ken
Takeda, Makoto
Kidokoro, Minoru
spellingShingle Katoh, Hiroshi
Kubota, Toru
Ihara, Toshiaki
Maeda, Ken
Takeda, Makoto
Kidokoro, Minoru
Cross-Neutralization between Human and African Bat Mumps Viruses
author_facet Katoh, Hiroshi
Kubota, Toru
Ihara, Toshiaki
Maeda, Ken
Takeda, Makoto
Kidokoro, Minoru
author_sort Katoh, Hiroshi
title Cross-Neutralization between Human and African Bat Mumps Viruses
title_short Cross-Neutralization between Human and African Bat Mumps Viruses
title_full Cross-Neutralization between Human and African Bat Mumps Viruses
title_fullStr Cross-Neutralization between Human and African Bat Mumps Viruses
title_full_unstemmed Cross-Neutralization between Human and African Bat Mumps Viruses
title_sort cross-neutralization between human and african bat mumps viruses
description Recently, a new paramyxovirus closely related to human mumps virus (MuV) was detected in bats. We generated recombinant MuVs carrying either or both of the fusion and hemagglutinin-neuraminidase bat virus glycoproteins. These viruses showed replication kinetics similar to human MuV in cultured cells and were neutralized efficiently by serum from healthy humans.
publisher Centers for Disease Control and Prevention
publishDate 2016
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806932/
_version_ 1613557474330148864

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