Autophagy in lung disease pathogenesis and therapeutics
Autophagy, a cellular pathway for the degradation of damaged organelles and proteins, has gained increasing importance in human pulmonary diseases, both as a modulator of pathogenesis and as a potential therapeutic target. In this pathway, cytosolic cargos are sequestered into autophagosomes, which...
Main Authors: | , |
---|---|
Format: | Online |
Language: | English |
Published: |
Elsevier
2015
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803789/ |