A CEP215–HSET complex links centrosomes with spindle poles and drives centrosome clustering in cancer

A CEP215–HSET complex links centrosomes with spindle poles and drives centrosome clustering in cancer

Numerical centrosome aberrations underlie certain developmental abnormalities and may promote cancer. A cell maintains normal centrosome numbers by coupling centrosome duplication with segregation, which is achieved through sustained association of each centrosome with a mitotic spindle pole. Althou...

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Bibliographic Details
Main Authors: Chavali, Pavithra L., Chandrasekaran, Gayathri, Barr, Alexis R., Tátrai, Péter, Taylor, Chris, Papachristou, Evaggelia K., Woods, C. Geoffrey, Chavali, Sreenivas, Gergely, Fanni
Format: Online
Language:English
Published: Nature Publishing Group 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802056/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802056/

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