Irradiation of necrotic cancer cells, employed for pulsing dendritic cells (DCs), potentiates DC vaccine-induced antitumor immunity against high-grade glioma

Irradiation of necrotic cancer cells, employed for pulsing dendritic cells (DCs), potentiates DC vaccine-induced antitumor immunity against high-grade glioma

Dendritic cell (DC)-based immunotherapy has yielded promising results against high-grade glioma (HGG). However, the efficacy of DC vaccines is abated by HGG-induced immunosuppression and lack of attention toward the immunogenicity of the tumor lysate/cells used for pulsing DCs. A literature analysis...

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Bibliographic Details
Main Authors: Vandenberk, Lien, Garg, Abhishek D., Verschuere, Tina, Koks, Carolien, Belmans, Jochen, Beullens, Monique, Agostinis, Patrizia, De Vleeschouwer, Steven, Van Gool, Stefaan W.
Format: Online
Language:English
Published: Taylor & Francis 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801426/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801426/

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