Single-cell analysis of transcription kinetics across the cell cycle
Transcription is a highly stochastic process. To infer transcription kinetics for a gene-of-interest, researchers commonly compare the distribution of mRNA copy-number to the prediction of a theoretical model. However, the reliability of this procedure is limited because the measured mRNA numbers re...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
eLife Sciences Publications, Ltd
2016
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801054/ |