3D-printed guiding templates for improved osteosarcoma resection

Osteosarcoma resection is challenging due to the variable location of tumors and their proximity with surrounding tissues. It also carries a high risk of postoperative complications. To overcome the challenge in precise osteosarcoma resection, computer-aided design (CAD) was used to design patient-s...

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Main Authors:	Ma, Limin, Zhou, Ye, Zhu, Ye, Lin, Zefeng, Wang, Yingjun, Zhang, Yu, Xia, Hong, Mao, Chuanbin
Format:	Online
Language:	English
Published:	Nature Publishing Group 2016
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800413/

id	pubmed-4800413
recordtype	oai_dc
spelling	pubmed-48004132016-03-22 3D-printed guiding templates for improved osteosarcoma resection Ma, Limin Zhou, Ye Zhu, Ye Lin, Zefeng Wang, Yingjun Zhang, Yu Xia, Hong Mao, Chuanbin Article Osteosarcoma resection is challenging due to the variable location of tumors and their proximity with surrounding tissues. It also carries a high risk of postoperative complications. To overcome the challenge in precise osteosarcoma resection, computer-aided design (CAD) was used to design patient-specific guiding templates for osteosarcoma resection on the basis of the computer tomography (CT) scan and magnetic resonance imaging (MRI) of the osteosarcoma of human patients. Then 3D printing technique was used to fabricate the guiding templates. The guiding templates were used to guide the osteosarcoma surgery, leading to more precise resection of the tumorous bone and the implantation of the bone implants, less blood loss, shorter operation time and reduced radiation exposure during the operation. Follow-up studies show that the patients recovered well to reach a mean Musculoskeletal Tumor Society score of 27.125. Nature Publishing Group 2016-03-21 /pmc/articles/PMC4800413/ /pubmed/26997197 http://dx.doi.org/10.1038/srep23335 Text en Copyright © 2016, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Ma, Limin Zhou, Ye Zhu, Ye Lin, Zefeng Wang, Yingjun Zhang, Yu Xia, Hong Mao, Chuanbin
spellingShingle	Ma, Limin Zhou, Ye Zhu, Ye Lin, Zefeng Wang, Yingjun Zhang, Yu Xia, Hong Mao, Chuanbin 3D-printed guiding templates for improved osteosarcoma resection
author_facet	Ma, Limin Zhou, Ye Zhu, Ye Lin, Zefeng Wang, Yingjun Zhang, Yu Xia, Hong Mao, Chuanbin
author_sort	Ma, Limin
title	3D-printed guiding templates for improved osteosarcoma resection
title_short	3D-printed guiding templates for improved osteosarcoma resection
title_full	3D-printed guiding templates for improved osteosarcoma resection
title_fullStr	3D-printed guiding templates for improved osteosarcoma resection
title_full_unstemmed	3D-printed guiding templates for improved osteosarcoma resection
title_sort	3d-printed guiding templates for improved osteosarcoma resection
description	Osteosarcoma resection is challenging due to the variable location of tumors and their proximity with surrounding tissues. It also carries a high risk of postoperative complications. To overcome the challenge in precise osteosarcoma resection, computer-aided design (CAD) was used to design patient-specific guiding templates for osteosarcoma resection on the basis of the computer tomography (CT) scan and magnetic resonance imaging (MRI) of the osteosarcoma of human patients. Then 3D printing technique was used to fabricate the guiding templates. The guiding templates were used to guide the osteosarcoma surgery, leading to more precise resection of the tumorous bone and the implantation of the bone implants, less blood loss, shorter operation time and reduced radiation exposure during the operation. Follow-up studies show that the patients recovered well to reach a mean Musculoskeletal Tumor Society score of 27.125.
publisher	Nature Publishing Group
publishDate	2016
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800413/
_version_	1613555289311674368

3D-printed guiding templates for improved osteosarcoma resection

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