Cyclic Stretch Facilitates Myogenesis in C2C12 Myoblasts and Rescues Thiazolidinedione-Inhibited Myotube Formation

Thiazolidinedione (TZD), a specific peroxisome proliferator-activated receptor γ (PPARγ) agonist, was developed to control blood glucose in diabetes patients. However, several side effects were reported that increased the risk of heart failure. We used C2C12 myoblasts to investigate the role of PPAR...

Full description

Bibliographic Details
Main Authors: Chang, Ya-Ju, Chen, Yun-Ju, Huang, Chia-Wei, Fan, Shih-Chen, Huang, Bu-Miin, Chang, Wen-Tsan, Tsai, Yau-Sheng, Su, Fong-Chin, Wu, Chia-Ching
Format: Online
Language:English
Published: Frontiers Media S.A. 2016
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800178/